permanent chromogenic labelling of DNA

Dr. Shirish A. Ranade S.Ranade at
Sat Jun 14 09:34:37 EST 1997

Dear Netters

I am interested in tracking some information on chromogenic labelling of 
DNA, something similar to say India ink-staining of proteins. However, 
this should not involve coupling of an enzyme to DNA and then assaying 
the enzyme with a chromogenic reaction. 

Also, suppose I were to mix some toluidine blue (a dye used earlier to 
stain DNA in gels) with DNA, what kind of stability the dye - DNA complex 
has or will have? Will dye be easily extracted from the DNA?

Is there some information available on these lines? If so, you could 
e-mail to me as follows :

E-mail to Wye College Until June 30 1997 only at

S.Ranade at

After July please e-mail to my permanent address in India at

sar at

Thanks in advance.


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