Well, You can check in the novagen home page: > http://www.novagen.com/ It is very well documented and includes maps, handbook and sequences Good luck Yvon CAVALOC UPR41 CNRS Faculte de Medecine 2, Av du Pr L Bernard 35043 RENNES Cedex cavaloc at sun-recomgen.univ-rennes1.fr tel +33 (0)2 99 33 62 47 Fax +33 (0)2 99 33 62 00