Shearing DNA

Karl Fischer tyr-2 at
Mon May 5 09:38:15 EST 1997

In article <5kj135$sft at>, iayork at (Ian A. York) wrote:


Have you considered (though you've likely tried these) generating
fragments using either a) sonication (titrated by time at a constant power
setting) or b) DNAse I (once again time titrated against a defined amount
of enzyme)???

Just some Monday morning thoughts....

karl the hepB guy

Karl Fischer
tyr-2 at

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