gluteraldehyde mechanism

Dima Klenchin klenchin at facstaff.REMOVE_TO_REPLY.wisc.edu
Wed Oct 15 20:24:37 EST 1997


In article <6206ij$sqc$1 at isnews.csc.calpoly.edu>, smccull at jurassic.fisher.calpoly.edu (The Kindly One) wrote:

#Can anyone tell me if gluteraldehyde(around 0.3% I think) will x-link
#DNA to proteins or will it selectively make protein-protein
#xlinks.

Yes it will crosslink proteins to DNA with _some_ efficiency. Can't be more 
specific.

#If not, anyone have ideas for prot-prot specific x-linkers????

I found Pierce's catalog/handbook to be a good starting point. 


-  Dima



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