Can dried-out DNA be dissolved ?

Geoffrey Kidd GKidd at
Wed Sep 24 14:52:28 EST 1997

I had this problem a long time ago, and to the best of my recollection, 
I could not dissolve the DNA no matter what I tried, which included 
using a homogenizer as a final resort.  But I wonder if an alkaline 
solution would work, since DNA is acidic?  Good luck!

Geoffrey Kidd

Edith Duerbaum wrote:
> Hi everybody,
> I´m working with genomic human DNA and ever so often I let it dry too
> long after isolation /alcohol wash.
> How can I dissolve my precious DNA which is supposed to dissolve in TE at
> 56°C, but sometimes just won´t ?
> Thanks for helping !

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