Dissolving Ciprofloxacin

Philip Hofstrand philiph at u.washington.edu
Tue Apr 14 10:27:05 EST 1998

In article <6gsn6b$8u2 at mserv1.dl.ac.uk>, "Mr. Chirag Joshi"
<chirag at cge.iisc.ernet.in> wrote:

>        1) How is Ciprofloxacin dissolved for use in tissue culture and 
>        2) What is the concentration generally used in tissue culture
>I have Ciprox. powder (as oral capsules, 250 mg) but it dosen't dissolve
>in PBS, Water, 0.85% NaCl, RPMI 1640 (at 1 mg/ml). Injectible solution
>(i/v) is available as 2 mg/ml solution in 0.9% NaCl. Does oral capsule in
>powder form contain any additives (not mentioned on the packet)? 

You can find all you want to know at RxList <http://www.rxlist.com/>,
including the consituents of the oral form (which is Ciprofloxacin HCl).
Table 5 will give you data about MICs in vitro. Hope this helps!

Phil Hofstrand

Philip Hofstrand                <philiph at u.washington.edu>
University of Washington        Research Technologist
Radiation Biology               Lab: NW 142 UWMC, (206)548-4094
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