inhibitors of DNA-binding proteins
dspinella at chugaibio.com
Tue Aug 25 15:27:08 EST 1998
> Hello all,
> Can anyone think of an example(s) where a small molecule (MW < 500) can
> inhibit a DNA-binding protein (e.g. transcription factors)?
> William Sun, Ph.D
> Metabasis Therapeutics, Inc. Phone: (619) 622-3930
> 9390 Towne Centre Drive FAX: (619) 622-5545
> San Diego, CA 92121 Email: william at alum.mit.edu
It seems to me that you'd have to count corticosteroids and synthetic
analogs like dexamethasone as molecules which fit this description, no?
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