Oxygene entry into cells
pillayc at biochem.unp.ac.za
Thu Feb 19 10:28:47 EST 1998
Whilst I know that oxygen is delivered to cells by haemoglobin, how does
this oxgen enter the cells ? Is this oxygen chanelled to the mitochondria
by intracellular carrier molecules ? Why does this oxygen not react with
cellular reducing agents (like glutathione) which are present at high
concentrations in the cytoplasm. Oxygen (O2) is a non-polar molecule, why
should it dissolve into the cytoplasmic mileu when it could easily dissolve
into the lipid bilayer ? If this is the case, would there not be a chance
of fatty acid oxidation ?
Any references would be greatly appreciated.
Dept. of Biochemistry
University of Natal
fax +27 331 260 5462
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