Predicting Coiled Coils from Protein Sequences
aek4 at york.ac.uk
Tue Jan 20 13:00:35 EST 1998
MacStripe is a program for the prediction and analysis of potential
coiled-coil regions in protein sequences. A new and much improved
version (2.0a1) is available to download now from:
(This site also has links to software for other platforms).
MacStripe is the ideal tool for anyone who wants to explore potential
alpha-helical coiled coils in the sequence of their protein. With a full
Macintosh interface, the results of analyses (raw data or publication
quality plots) can easily be exported to other software. The "Inspector"
window acts like a magnifying glass so you can study your protein on a
residue-by-residue basis. MacStripe uses the algorithm of Andrei Lupas's
COILS2 for detailed and reliable coiled-coil predictions.
System Requirements: Macintosh with 68030, '040 or PowerPC processor;
Colour Quickdraw; System 7.0 or better.
* Full Macintosh Interface
* Uses established Lupas algorithm for coiled coil prediction
* Full control of prediction parameters (matrix, window length,
* Interactive exploration of coiled coil with "Inspector" window
* Imports sequences from DNA Strider or DNASTAR formats
* Reads sequences from text files in plain, FASTA or Staden formats
* Uses FPU (where present) for maximum calculation speed
* Plots optionally show 'skips' or 'stutters' in coiled coil which may
be structurally important
* Plots can be copied and pasted into other applications, saved as PICT
files, or printed
* Detailed statistics can be imported into spreadsheet or graphing
* It's FREE!
Please don't hesitate to contact me with suggestions, bug reports or
complaints. Don't forget to check out the coiled-coil prediction web
page for more information about MacStripe or other coiled-coil
Alex Knight (aek4 at york.ac.uk)
University of York
Heslington, York Y01 5DD
+44 1904 434381
+44 1904 432860 (FAX)
Molecular Motors Web Page:
Coiled coil prediction web page:
More information about the Methods