Factor Xa p1' specificity

Lena Zaitseva zaitseva at biochem.purdue.edu
Wed Jun 10 08:58:31 EST 1998



Rob Linning wrote:

> Hello. We are designing a protein using a Factor Xa site to introduce a
> specific amino acid residue at its N-terminus. Does anyone have any
> information on the effect on Factor Xa cleavage efficiency of different
> amino acids residues at the IEGR-P1' position? Thanks in advance for any
> info or help. Rob Linning (rlinning at sfu.ca).

    Check "Methods in Enzymology", vol.153, pp.461-481 (p.478 - table which
summarizes cleaved sequences).     Lena.





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