searching for HLA negative cell line
Ian A. York
iayork at panix.com
Thu Nov 5 16:30:46 EST 1998
In article <3.0.32.19981105144541.00704cb8 at imm2.imm.uth.tmc.edu>,
David L. Haviland, Ph.D. <dhavilan at IMM2.IMM.UTH.TMC.EDU> wrote:
>
>Going strictly from memory, Daudi (B cell) and K562 (erythroleukemic) come
>to mind as Class-I negative. I also have it in my advisors handwriting
>(from *many* moons ago) that the B cell line Raji is also Class-I negative.
K562 are HLA negative, Raji are not. You need to be careful with studies
on K562, because they upregulate their MHC when treated with interferon
(and various other things). I don't know whether they have non-classical
class I.
Ian
--
Ian York | I find that I have,
iayork at panix.com | as a result of this post,
http://www.panix.com/~iayork/ | grown to hate haiku --Jennifer Mullen
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