ss RNA ligase

Daniel.Marc marc at
Tue Nov 17 11:11:33 EST 1998

Esbjorn Fiers (esfie at wrote:
: > Dear Geert,

: I don't think such a thing like ssRNA ligase exists!

Why not?
In my opinion, such an activity is present in spliceosome, and one can imagine
that ribozymes, which can cleave ssRNA substrates, may be capable of
the reverse reaction under certain conditions (although of course
their substrate are highly sequence-specific).

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