Random deletion in gene

ChenHA hachen at bc.ic.ac.uk
Sun Aug 15 10:48:27 EST 1999


I'm interested in finding out how to detect folded domain in a
protein, and one way may be to randomly delecting part of a gene,
whether of the N-termius, C-terminus or internal section of its
protein.  I wonder if anyone has any information on how to
do random deletion of this sort, one that could generate large number
of different DNA constructs for further analysis.  Any reference or
suggestion would be gratefully received.




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