in vitro Knock out

Pierre Rodrigues pirod at
Sun Aug 22 11:06:26 EST 1999


I was wondering if there is a way to perform a gene knock out in a cell
culture without going on the mouse. Just to make an homologous
recombination and select resistant clones which would be knocked out in
a gene...

Is there anybody out there which has a clue?


Pierre Rodrigues
Institut Pasteur

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