Multiple amino acid mutagenesis

mb mb at laplace.csb.yale.edu
Sat Nov 13 16:07:04 EST 1999


try going to the below site and running the basic homology search,
alignment and prediciton routine.  This should give you a rational basis
for deciding what to do.  Pay close attention to both the structure
prediction and the exposed/buried prediction.  This should give you an
idea of what a given mutation may do.  You can even run the predictions
with potential mutated sequences.  There may also turn out to be
homologous domains of known structure.


http://dodo.cpmc.columbia.edu/predictprotein/


--
Mark Bowen







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