Multiple amino acid mutagenesis

mb mb at
Sat Nov 13 16:07:04 EST 1999

try going to the below site and running the basic homology search,
alignment and prediciton routine.  This should give you a rational basis
for deciding what to do.  Pay close attention to both the structure
prediction and the exposed/buried prediction.  This should give you an
idea of what a given mutation may do.  You can even run the predictions
with potential mutated sequences.  There may also turn out to be
homologous domains of known structure.

Mark Bowen

More information about the Methods mailing list