What is a concatomer?

Frank O. Fackelmayer Frank.Fackelmayer at uni-konstanz.de
Sat Nov 20 07:25:08 EST 1999



"Bernard Murray, PhD" wrote:

> In article <2750ac20.f0ed247a at usw-ex0107-043.remarq.com>, susanne
> <srohrerNOsrSPAM at immv.unizh.ch.invalid> wrote:
>
> > A concatemer is a number of DNA segments joined to each other by
> > overlapping ends. Bacteriophage lambda, e.g. makes concatemers.
>
> I would normally refer to that as a tandem-repeat or multimer.
> I don't dispute the above definition but I've also seen concatamer used
> to describe circular pieces of DNA joined in a literal chain-like
> manner (two *separate* circles interlinked).
>    I'll be happy to be corrected...

chain-like interconnected DNA circles (like e.g. plasmids incompletely
separated after replication due to limiting gyrase activity) are usually
referred to as CATENANES, not concatemers. Concatemers are linear
multimers of the same DNA molecule, as pointed out by the other posters
before.

Frank





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