Try http://www.neb.com/ftp_info/software/silmut/ Student <mucineer at iname.com> wrote in message news:81b90m$nfr$1 at oyez.ccc.nottingham.ac.uk... > Does anyone know if there is a computer program available for download that > can scan a dna sequence and allow you to engineer restriction sites by > changing codon usage? > > >