using UV absorbance scans to 'measure' homogeneity of proteins

[Robert Presswood]

David wrote:

> Hi,
>
> I've heard that one can tell from the UV absorbance scan of a protein
> solution, whether it is likely to be homogeneous or not. I'd be grateful
> for any comments on this method, e.g. what features of the scan one should
> look for, and how reliable this method is.
>
> Thank you very much in advance,
>
> David

The UV absorbance spectrum would not be an adequate criterion.