In our lab we have been trying to generate alpha-beta T-cell receptors
expressing the both alpha and beta chains in bacterias and mix them to
generate the heterodimer molecule but with poor susccess. I read
recently that putting the fos/jun leucine zippers (LZ) you are able to
do that. My question is: does anybody cloned in a plasmid the DNA
coding for that two molecules (fos-jun) or for just the LZ, and is
possible to send me some of those plasmids?.
If anybody can help me on this subject please contact me on:
ruben.varela-calvino at kcl.ac.uk
Thank you very much.
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