effect of DMSO on pH

Bernard Murray, PhD spam at 127.0.0.1
Fri Mar 17 22:30:08 EST 2000


In article <852568A5.00766F9D.00 at baltmta01.ms.bd.com>,
Bill_A_Nussbaumer at ms.bd.com wrote:

> Bill A Nussbaumer at BDX
> 03/17/2000 04:44 PM
> 
> Hi all,
> 
> Does anyone have any information or experience regarding the effect on
pH vs the
> effect on a pH meter when DMSO is added to a buffer?  Actual data, references,
> theories, and postulations all welcome.

If handwaving is permitted, then.....

DMSO is an aprotic solvent.  Therefore pure DMSO shouldn't
change the pH at all (but watch those contaminants!).

   How did I do?

   Bernard

-- 
Bernard P. Murray, PhD
bpmurray at cgl . ucsf . edu
Department of Cellular & Molecular Pharmacology, UCSF




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