effect of DMSO on pH

J. Martinez-Irujo jjmirujo at unav.es
Sat Mar 18 03:59:46 EST 2000


"Bernard Murray, PhD" wrote:

> In article <852568A5.00766F9D.00 at baltmta01.ms.bd.com>,
> Bill_A_Nussbaumer at ms.bd.com wrote:
>
> > Bill A Nussbaumer at BDX
> > 03/17/2000 04:44 PM
> >
> > Hi all,
> >
> > Does anyone have any information or experience regarding the effect on
> pH vs the effect on a pH meter when DMSO is added to a buffer?  Actual data,
> references, theories, and postulations all welcome.
>
> If handwaving is permitted, then.....
>
> DMSO is an aprotic solvent.  Therefore pure DMSO shouldn't
> change the pH at all (but watch those contaminants!).
>
>    How did I do?
>
>    Bernard
>
> --
> Bernard P. Murray, PhD
> bpmurray at cgl . ucsf . edu
> Department of Cellular & Molecular Pharmacology, UCSF

What about the effect of DMSO on dielectric constant? It was also reported that DMSO
forms stable coordination complexes with metals.

--
Juan Jose Martinez Irujo
Departamento de Bioquimica
Universidad de Navarra
Spain


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