proteasome/luciferase

Alain Kohl akohl001 at udcf.gla.ac.uk
Thu May 18 10:35:43 EST 2000


Dear All,
does anybody know if proteasome inhibitors such as MG132 have an effect on
renilla or firefly luciferase? We are using those genes as reporters and
observe activity decrease even after short incubations with MG132...it's a
bit a mistery to us right now, so if anybody knows which secundary effect
of MG132 might be responsible, let me know.

Thanks
Alain
Dr Alain Kohl
Division of Virology
University of Glasgow
Church Street
Glasgow G3 6LF
Scotland, UK
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