J. Martinez-Irujo jjmirujo at unav.es
Tue May 30 03:15:48 EST 2000

"M.P.J. de Winther" wrote:

> Hi,
> I would like to induce apoptosis in cultured mouse macrophages. Tried 1
> microM dexamathasone but that does not seem to work.
> Any suggestions?
> Thanks,
> Menno de Winther

2-10 uM camptopthecin, a topoisomerase inhibitor, is another option. Is
sometimes used as positive control in some kits to detect apoptosis.

Juan J. Martínez Irujo

Departamento de Bioquimica
Universidad de Navarra
Pamplona, Spain

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