Converting micrograms to moles for IgG

clarosa clarosa at biocomp.unl.edu
Mon Nov 13 14:41:48 EST 2000


yes 1 mole is about 150 kDA..given that the size is an estimate.

Student wrote:

> This may sound a very silly question to many of you. Whilst I know how to
> convert mass to moles for small molecules, I have never done it for large
> proteins. For an IgG1 molecule, I know the size is approximately 150kDa.
> Does this mean that 1 mole = 150,000grams? (It would be rather tedious to
> add up all the molecular weights of the amino acids to get the molar mass!)
>
> Thanks, and excuse my ignorance!






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