Signalpeptide I versus II

Per Holse Mygind perm at biobase.dk
Wed Oct 4 09:31:57 EST 2000


Concerning a bacterial membrane protein

One of the proteins that I work with seems contain both a predictable
signal peptidase I and II cleavage at different sites.
Both type of signal peptides are translocated across the inner membrane
via the SEC apparatus. Can anybody tell me what happens to the protein ?
Which peptidase cleaves this protein ?
Has such prediction been observed for other proteins ?

The first 70 aa are: MQTSFHKFFL SMILAYSCCS LSGGGYAAEI MIPQGIYDGE
TLTVSFPYTV IGDPSGTTVF SAGELTLKNL

Kind regards

Per Holse Mygind
University of Aarhus






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