Endotoxin in DNA Vaccines

drdlmartin at my-deja.com drdlmartin at my-deja.com
Fri Oct 6 17:07:28 EST 2000

What is the highest level of endotoxin acceptable for DNA to be used
for injection in  murine models?  We have tried several systems to get
rid of the endotoxin from our bulk prep, as well as Qiagen Endofree
kits, but our endotoxin levels are consistently around 10 mcg/mg DNA.

Diana Martin

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