Best machine for in situ PCR

Dr. Duncan Clark Duncan at
Thu Oct 19 03:40:25 EST 2000

In article <8slu6c$625$1 at>, the eminent Rick A. Bright
at Emory University wrote
>The licensing status of the thermocycler has no relevance if you use
>licensed reagents (which is almost impossible to avoid).

Wrong. When you buy licensed PCR reagents you are buying a limited
license to practice PCR only for research and development use and only
then for use on authorised PCR machines.

Full license disclaimer is.


A license under U.S. Patents 4.683.202, 4.683.195 and 4.965.188 or their
foreign counterparts, owned by Hoffmann-La Roche Inc. and F. Hoffmann-La
Roche Ltd ("Roche"), has an up-front fee component and a running-royalty
component. The purchase price of this product includes limited,
nontransferable rights under the running-royalty component to use only
this amount of the product to practice the Polymerase Chain Reaction
("PCR") and related processes described in said patents solely for the
research and development activities of the purchaser when this product
is used in conjunction with a thermal cycler whose use is covered by the
up-front fee component. Rights to the up-front fee component must be
obtained by the end user in order to have a complete license. These
rights under the up-front fee component may be purchased from Perkin-
Elmer or obtained by purchasing an Authorized Thermal Cycler. No right
to perform or offer commercial services of any kind using PCR, including
without limitation reporting the results of purchaser's activities for a
fee or other commercial consideration, is hereby granted by implication
or estoppel. Further information on purchasing licenses to practice the
PCR Process may be obtained by contacting the Director of Licensing at
The Perkin-Elmer Corporation, 850 Lincoln Center Drive, Foster City,
California 94404 or at Roche Molecular Systems, Inc., 1145 Atlantic
Avenue, Alameda, California 94501. 


The problem with being on the cutting edge is that you occasionally get 
sliced from time to time....

Duncan Clark
GeneSys Ltd.
Tel: +44(0)1252376288
FAX: +44(0)8701640382

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