how to show unspecific protein-DNA complexes???

Frauke Naumann fnaumann at
Wed Sep 20 03:07:22 EST 2000

Hi netters,
a collegue of mine wants to show that protamin forms a complex with a
plasmid of 4.2 kb. For EMSA the DNA fragment should be too big, and anyway,
EMSA might only apply for specific protein-DNA complexes????
Is there an easy protocol for showing that a complex is formed???????
Thanks for any information,

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