humanizing a gene

Emir Khatipov khatipo at ZAPuchicago.edu
Fri Aug 17 19:27:09 EST 2001


I suggest "colificating".
Seriously, I think what you are doing is adaptation of E.coli codon usage to
a Pseudomonas gene. Why design a new term?

-Emir


"Michael Witty" <mw132 at mole.bio.cam.ac.uk> wrote in message
news:Pine.SGI.4.33.0108161318470.4915564-100000 at mole.bio.cam.ac.uk...
> Dear All,
>         if I was taking a heterologous coding sequence and making all the
> rare codons into human preferred codons I would be humanizing the coding
> sequence.  BUT I am taking a Pseudomonas coding sequence and making all
> the rare codons into E. coli preferred codons.  What should I call this?
>
> Escherichizing?  Colizing?  Colonizing?  Please help with my genetic
> grammar.  Mike.
>





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