What does "pca" in a protein sequence mean??

Luis M. Sanchez lmsp at correo.uniovi.es
Sat Feb 17 10:11:21 EST 2001

PCA: pyroglutamic acid (http://xray.bmc.uu.se/hicup/). When glutamine is the
N-terminal residue, it usually gets cycled to pyroglutamic acid. It can
occur without any enzyme but at least the eukaryotes have an enzyme that
catalyzes the reaction.

Luis M. Sanchez
Department of Biochemistry
University of Oviedo
Oviedo 33006

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