Post-translational transfer into ER?
Ian A. York
iayork at panix.com
Wed Mar 28 12:46:23 EST 2001
Is there a way to reliably load peptides into the lumen of the ER,
post-translationally? What we'd like to do is load cells (by osmotic
loading) with a peptide, and compare effects when it's in the cytosol and
when it's in the ER. I have a vague memory of some bacterial toxin that
targets ER, but it is, alas, too vague to actually be useful.
Ian York (iayork at panix.com) <http://www.panix.com/~iayork/>
"-but as he was a York, I am rather inclined to suppose him a
very respectable Man." -Jane Austen, The History of England
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