local charges of peptide chain

[Sergio]

At the following URL you can obtain the tritaion curve of any peptide/protein.
Maybe sending fragments of the protein sequence would be a good start....??

Sergio

Wolfgang Schechinger ha escrito:

> Hi all,
>
> I would like to compare local charges of related proteins at different pH
> (e.g. if Tyrosines are likely to be protonated or not at a certain pH).
> A series of plots showing LOCAL positive/negative/zero charge is what I would
> like to get. But I am NOT looking for a standard isoelectric plot since that
> would only refer to the overall net charge.
>
> Before I start programming, is anyone aware of such a tool?
>
> Thanks and Regards,
>
> Wo
>
> -----
> Dr. Wolfgang Schechinger
> Institute of Biomedical Sciences
> Academia Sinica, Taipei, Taiwan R.O.C.
> e mail wolfsc at ibms dot sinica dot edu dot tw
> -----
>
> ---