Web site to predict Tm of hairpin RNA

Austin So (Hae-Jin) haejin at netinfo.ubc.caX
Fri Oct 26 19:46:00 EST 2001


"Carmelo" <carmelo.diprimo at bordeaux.inserm.fr> wrote in message
news:261020010924481678%carmelo.diprimo at bordeaux.inserm.fr...
> > Those Zuker guys are more interested into structure than into Tm.
> > Why do you want to know? Hairpins should have a low Tm anyway.
>
> Well I just wanted to compare the Tm of a hairpin which do not depend
> on concentration versus the tm of its duplex stem which will depend on
> concentration.

Tm of DNA hairpins are higher than the corresponding duplex. There is no
reason to believe that it would be different for RNA.


--
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Austin P. So (Hae Jin)

I.I.S.G.P.
Biotechnology Laboratory
University of British Columbia

E-mail: haejin at netinfo.ubc.ca
http://server1.biotech.ubc.ca/~austin/





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