Web site to predict Tm of hairpin RNA

Austin So (Hae-Jin) haejin at netinfo.ubc.caX
Fri Oct 26 19:46:00 EST 2001

"Carmelo" <carmelo.diprimo at bordeaux.inserm.fr> wrote in message
news:261020010924481678%carmelo.diprimo at bordeaux.inserm.fr...
> > Those Zuker guys are more interested into structure than into Tm.
> > Why do you want to know? Hairpins should have a low Tm anyway.
> Well I just wanted to compare the Tm of a hairpin which do not depend
> on concentration versus the tm of its duplex stem which will depend on
> concentration.

Tm of DNA hairpins are higher than the corresponding duplex. There is no
reason to believe that it would be different for RNA.

Austin P. So (Hae Jin)

Biotechnology Laboratory
University of British Columbia

E-mail: haejin at netinfo.ubc.ca

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