how to remove abasic ( without base) site from DNA

tarang tkhare at yahoo.com
Thu Apr 18 05:00:05 EST 2002


hi,
In vivo misincorporation of uracil in DNA is repaired by uracil
glycosylase and by AP endonucleated activity. While in vitro Uracil
glycosylase can remove the uracil base but how to remove abasic site.
Any idea???????
Waiting for early reply
tarang




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