Intro to mouse handling and genetics?

Frank O. Fackelmayer Frank at
Tue Dec 10 11:33:34 EST 2002

a look at

might help a lot.


"Ian A. York" wrote:
> My wife is halfway through making her first KO mouse.  While trying to
> plan out her next steps, she keeps running into little things that
> all the mouse people take for granted, but that she isn't familiar with;
> as well as some of the big things.  What she wants is a mid-sized,
> medium-priced book that goes through mouse handling in some detail, with
> particular emphasis on transgenics and knockouts.
> It doesn't have to be a book, but she hasn't found what she wants (i.e.
> the right degree of detail) on the web yet.  She can stick it on her
> boss's grant if it's less than $50; so far she's only found a $200 book,
> and her boss won't let her order it.
> Some of the things she complained about to me, were not knowing at what
> age you can breed a mouse, how many is an average litter size, and what
> average goes from the chimeras to germline.  These things have all been
> answered now, but give examples of the levels of questions she wants
> answered.
> Any suggestions?
> --
>     Ian York   (iayork at  <>
>     "-but as he was a York, I am rather inclined to suppose him a
>      very respectable Man." -Jane Austen, The History of England

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