Latex beads for binding negatively charged protein?

Wolfgang Schechinger wolfsc at
Thu Mar 21 10:02:39 EST 2002

Dear Josephine,

Hmmmm. What about chemically activated reactive ones? Or might bifiunctional 
coupling reagents (see e.g. Pierce's catalogue) do the job?

Could activated sepahrose beads or some microspheres pinched from the 
combinatorial freaks (Sigma, Novachem, others) be a considerable alternative?

Just some thoughts. 



> Hi
> Have anybody tried to use latex beads, to bind a negatively charged 
> protein? Usually the hydrofobic sites of the proteins bind to latex beads,
> right? If you now about any latex beads with a positively charged surface,
> please give me a hint!
> Josephine Wernersson
> Dep.of odontology
> Umea University
> Umea, Sweden
> ---

Dr. Wolfgang Schechinger
Institute of Biomedical Sciences
Academia Sinica, Taipei, Taiwan


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