DNA fragmentation after long treatment with alkali

Wolfgang Schechinger hubahopp at gmx.de
Thu Nov 21 06:36:49 EST 2002


did you run a sample on gel? What does it look like? Do you need to rescue
something? Did you do it on purpose and what's your goal?
Depending on pH and strength of the base (NaOH?) there's probably not much
more than broken backbones and derivatized nucleotides.

Would you like to give us some more details?


At 10:41 AM 2002/11/21 +0100, Fabio wrote:
>Please does anyone have some references about DNA fragmentation after
>treatment with alkali foor long time (12 h-days)?
>thankyou in advance


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