Post-transcriptional regulation, why?

Philipp Wechner philipp.wechner at uibk.ac.at
Mon Sep 9 04:27:29 EST 2002


There would be no post-transcriptional regulation if there was no need for
it.
But it is an important part of the regulation!


Trond Erik Vee Aune schrieb:

> Hi again,
>
> Why is there a need for post-transcriptional regulation (PTR) when the
> expression could be regulated on transcription level alone? By making
> unnecesarry mRNA the cell is obviously wasting energy. I would think
> that adjusting the strength of the promotor coupled with transcription
> regulators would be sufficient to regulate the expression to appropriate
> levels. Perhaps it costs more to make regulators? But in some cases it
> seems even constitutively expressed proteins are regulated on RNA level.
> Does anyone have any ideas to why cells have developed PTR?
>
> Kind regards,
> Trond Erik Vee Aune




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