How to inactivate proteins in organ extracts?

[Dr Engelbert Buxbaum]

WS wrote:

> Dear Experts!
> 
> How to inactivate proteins in an aqueous organ extract? 

Aceton-precipitation, alternatively methanol or phenol. Trichloroacetic
and sulphosalicylic acid. You'l probably have to use several methods as
your mysterious substance could be precipitated/inactivated. 

Alternatively, use ultrafiltration or dialysis to separate small
molecules and check for activity.