Does the postPCR 4-degree hold damage the thermal cycler ??

[arnaud.garcon at syngenta.com]

> 
> Completely unecessary anyway; samples have already been 
> cycled to 94 degrees 30 or so times, sitting at rt overnight 
> doesn't harm your samples one bit.
 
A good point, but what if you're using a proof reading polymerase with
exonuclease activity. Don't you risk your product being chewed up?

A.-