SENIOR RESEARCH & DEVELOPMENT CHEMIST - Torrance, CA
resumes at workwondersstaffing.net
Thu Sep 7 14:01:02 EST 2006
Seeking a Senior R&D Chemist for a biochemical company located in
Torrance, CA. Below is more information concerning the opportunity, the
company and how to apply.
Reports to: Director, Research
Department: Research & Development
The Senior Research and Development Chemist has acquired experience in
Solid Phase Peptide Synthesis, with experience both in Boc and Fmoc
chemistry. The candidate should have hands on experience with manual
SPPS under cGMP conditions and is willing to apply know-how in SPPS to
the automation of peptide synthesis using the department Automated
Large Scale Peptide Synthesizer (CsBio). As a member of the Research
and Development team will conducts or supervises developmental
synthesis of new API, designs in coordination with the Director of
Research new purification strategies and implements them. Basic
knowledge of GMP procedure the Sr R&D Chemist to design and execute
processes easily transferred to cGMP production. Attention to details,
excellent procedure recording, and good communication skills facilitate
the transfer of these processes to production.
Supervise large scale manual SPPS of new R&D projects and/or cGMP early
Develop a process to use the automatic SPPS under GMP regulation.
Design, conduct or supervise new R&D purification procedure.
Contribute to the good organization of the common spaces of the R&D
Contribute to the maintenance and troubleshooting of analytical HPLC
and preparative HPLC.
Evaluate performance of staff and train staff.
Write process description and transfer of developed strategies to
Document analytical results for the benefit of production and other
Write analytical reports and summaries.
BS in Chemistry with at least two years experience in a GMP accredited
peptide production company, or lower chemistry degree (e.g. Chemical
Technical College) with at least four years experience in a GMP
accredited peptide synthesis company.
Good English skills, both written and oral.
EXPERIENCE & QUALIFICATION:
Hands on experience with solid phase peptide synthesis (manual),
automatic SPPS optional.
Two- plus years experience in peptide analysis (RP-HPLC) and
purification (preparative RP-HPLC, IEC-HPLC).
Previous experience in industry is a must.
Thorough understanding of peptide synthesis.
Thorough understanding of peptide purification.
Creativity to solve technical and analytical problems.
Enthusiasm and dedication.
Good communication and presentation skills.
Self-driven and independent.
Ability to set priorities and to follow through on commitments.
Safe and proficient laboratory practice.
Supervise one or multiple technicians.
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More information about the Methods