embryo powder

[Ed Siefker]

We're going to be making some embryo powder for antibody preabsorption
for in situ hybridization.  Pretty much as per this protocol:
http://www.oup.co.uk/pdf/pas/12-4-5.pdf

We're wondering whether it's ok to pulverize the embryos in liquid nitrogen
before homogenization in PBS.  I'm not sure our homogenizer would be able
to handle whole embryos.  That's not going to affect the antigenicity of the
embryo powder, is it?