Cytoclear a novel way to remove cytoplasm and hence improve prob signals

sturt via (by stuarthold from
Fri Nov 5 21:52:55 EST 2010

Cytoclear is a product we have successfully used over a few years
which can effectively dissolves and remove cytoplasm around mamalian &
human cells. In particular, according to the cimpany's literature:
"it dissolves the lipid and glycoprotein structure of which cytoplasm
is mainly composed. Clumped metaphases that would normally be
impossible to analyse can now be restored. Cytoclear is a useful tool
in FISH hybridizations as it enables the probe to reach the target DNA
by removing barrier cytoplasm surrounding the cell."

The company link to Cytoclear is below, i highly recommend it and
worth a go

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