Biotinylating a Drug

Yvonne Couch via methods%40net.bio.net (by yvonne.couch from pharm.ox.ac.uk)
Fri Jun 3 07:22:58 EST 2011

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Hi all,
I've been trying out some autoradiography using a 3H labelled version of citalopram (serotonin re-uptake inhibitor).  It takes weeks to do and we don't have the radioactive capacity to get a hotter radioactive isotope.  I was wondering whether anyone knows whether its possible to biotinylate something like citalopram and label tissues that way?
Regards
Yvonne

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