denis guenette via (by dkguenette from
Fri Jun 24 08:13:12 EST 2011

There is a new transfection reagent called Gylcofect. It is a poly-
glycoamidoamine (PGAA) polymer. Techulon=92s non-lipid reagent
encapsulates nucleic acid and delivers as polyplex with caveolae and
clathrin mediated uptake (1). These polymers are designed to hydrolyse
upon endocytosis, thereby increasing plasmid delivery with lower

Improving Transgene Expression and Cell Viability Using a
Biodegradable Polymeric Delivery Platform

Novel Twist on Primary Cell Transfection, Biodegradable Polymer-Based
DNA Carrier Designed to Facilitate Process in Mammalian Cells

See for yourself how we can deliver your genes of interest.

denis.guenette from
Office number: 540-443-9254


1. McLendon P.M. et al., Poly(glycoamidoamine) Vehicles Promote pDNA
through Multiple Routes and Efficient Gene Expression via Caveolae-
Mediated Endocytosis. Molecular Pharmaceutics 2010 Vol. 7(3), 738-750.

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