prostatitis culture case

Robert Morrell Jr. bmorrell at ISNET.IS.WFU.EDU
Thu Oct 27 07:46:03 EST 1994


On 26 Oct 1994, BCapstone wrote:
> I asked for data that shows that imipenem penetrates the prostatic fluid. 
> I want direct measurements of imipenem in the prostatic fluid.  I would
> also like to see a study that concludes that imipenem is effective against
> prostatitis.  You have not provided that data.
> 
> <Actually this would be remarkably easy to test, with a simple serial 
> micro tube dilution of the fluid (filtered) in  mueller hinton broth to 
> check for inhibition of a stock organism with a known MIC to imipenem.>
> 
> Do it. 
>
Need I remind you that =you= are the one questioning the penetration of 
imipenem. =I= am not going to waste my time on an experiment whose 
outcome is not in doubt.

You wanted sources: For the penetration of imepenim into prostate tissue:
Current Theraputic Research 1989, vlo 46 pg 614-618
for successful therapy of bacterial prostatitis using imipenem: three
Journ of Antimicrobial therapy 1986 Dec. 175-179
Japanese Journ of Antibiotics 1986 Apr. 39(4) 996-1006
Journ of Japanese Ass. for Infect. Diseases 67(2) 154-162 1993 feb

Now this raises a point that has been bothering me and others concerning
this thread. You claim to be a doctor that knows a lot about prostatitis,
yet you challenged me on the well known and readily available info of
imipenem's effectiveness in prostatitis (it took me all of two minutes to
find those three references) Exactly what does your knowledge of
prostatitis consist of, and how deep has your research gone, if you are
challenging something so easily obtainable?

 Furthermore, you claim to be a doctor in charge of a patient with
prostatitis and sepsis treated with imipenem. If you or the consult team
were unaware of imipenem's activity in the prostate, and, as you have
said, you believed the source of infection was the prostate, why did you 
prescribe it? Exactly what are the standards of care like in Chicago? 

I and several others have responded to your questions on and off the 
list, sending you reference meaterials, that addressed many of the 
questions you continue to pose even after they have been 
answered repeatedly. Several of us on this list have noted your 
persistantly anti-logical, seemingly willful ignorance on the subjects of: 
microbiology, antibiotics, scientific theory and logic, and ultimately, 
prostatitis. 

The question has arisen, are you who you claim to be: Dr. Bradley
Hennenfent of Chicago? Or are you one of the following:

 1. A lawyer doing research (unlikely, because a lawyer would know better 
    than sign a false name on s-mail.)
 2. A patient investigating his own case.
 3. A novelist gathering material. (This was AOL's idea)
 4. An incredibly stubborn, pig-headed and ignorant physician. 

My vote is on 4, but I am open to other theories.

*                     Bob Morrell                       *
*               bmorrell at isnet.is.wfu.edu               *
*       Taking offense is the last refuge of denial.    *




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