glycerol vs glucose

Forday Wayne Lee fwl at titan.np.ac.sg
Mon Dec 11 02:22:32 EST 1995


In article <DJ8HBE.5ys at cix.compulink.co.uk>,
:>> 
:>> Super-rich media recipes for growth of E coli typically include 
:>glycerol but
:>> not glucose.  Anyone know why?
:>> 
:>> Thanks,  Pete
:>This is not an answer but is there a possibility that it is connected 
:>with water activity ?
:>Peter Harris,
:>University of Reading, U.K.
:>

It may be something to do with the Glucose effect. Under high glucose
concentrations, E. coli switches to fermentation mode, regardless of the
oxygen concentration. I think the factor most influential is the
concentration of FDP. Perhaps glycerol leads to lower FDP concentrations and
thus pushes the cells to respire.

An interesting experiment.




-- 
Wayne Lee Forday, Biotechnology Department 
Ngee Ann Polytechnic, Singapore 
fwl at np.ac.sg
Fax:467-9109



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