Stability of Amplicillin

Anomie anomie at
Thu Sep 28 19:25:58 EST 1995

I'm doing a project on charactrerisation of B-lactamases. Recently, we tried to do enzyme kinetics using amplicillin as substrate. However we found out that amplicillin has a very high autohydrolysis rate. Can anyone out there provide me with the answer on how to improve the stability of the antibiotic?

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