5-fluoroorotic acid

Colin Rattray crattray at uoguelph.ca
Sat Mar 16 19:55:45 EST 1996


Any information concerning the use 5-fluoroorotic acid (5-FOA) in media 
for nutritional studies in bacteria would be much appreciated. I think I 
know where it fits in the uridine biosynthesis pathway but am having 
trouble with the mechanics of the stuff. Is it safe to autoclave the 
media with the FOA in it? Merck lists solubility as 1.7mg/ml but is it 
possible to get a more concentrated solution? Thanks.




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