PhD Studentship - Poultry Vaccine Development at Central Veterinary Laboratory

p m bramley p.bramley at
Fri May 31 10:24:58 EST 1996

Royal Holloway - University of London
Division of Biochemistry, School of Biological Sciences


The Bacteriology Department of the Central Veterinary Laboratory has many 
years experience in the development of bacterial vaccines for the 
protection of poultry.  A new research initiative, co-sponsored by the 
British Egg Marketing Board (BEMB) and Hoechst Animal Health (UK) Ltd, is 
the development of a genetically engineered Salmonella based multivalent 
live attenuated vaccine to deliver heterologous antigens, which in this 
model system, will use specific antigens from colisepticaemic Escherichia 
coli 078.  This broad project will employ recombinant DNA technologies to 
create vaccine candidates, a range of immunological techniques to monitor 
responses in the chicken and challenge models to test the efficacy of 
vaccine candidates.  The successful candidate will join an experienced 
mutli-skilled team with full training and support given.

This project demands an exceptional graduate with a proven aptitude for 
multifaceted research.  Ideally, applicants should possess (or expect to 
obtain in the current academic year) a veterinary qualification or a good 
first degree plus a masters degree in a relevant subject area such as 
applied biology, molecular biology, pathobiology, biochemistry, etc.  
Animal work is an essential component of the project.

Academic fees and remuneration of £11,000 pa will be paid for the 
duration of the project(3 years).  The start date will be by agreement 
but no later than September, 1996.  Registration will be with Royal 
Holloway and the supervisor will be Dr M J Woodward, Head of Molecular 
Genetics, CVL, from whom further scientific details may be obtained (tel: 
01932 357582, e mail: mwoodward.cvl.wood at

Applications, in the form of a curriculum vitae, with the names of at 
least two referees, should be sent to Prof P M Bramley, Division of 
Biochemistry, School of Biological Sciences, Egham Hill, Egham, Surrey, 
TW20 0EX, to arrive no later than June 24th, 1996.

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